Inhibition of RNA slow viruses by thiosemicarbazones

Ashley T. Haase; Warren Levinson

doi:10.1016/0006-291X(73)90008-9

Inhibition of RNA slow viruses by thiosemicarbazones

Ashley T. Haase, Warren Levinson

Microbiology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

N-methyl isatin β-thiosemicarbazone (Methisazone) effects comparable reductions in the reverse transcriptase activity and the cytopathic effect of the RNA slow viruses, Visna, Maedi and Progressive Pneumonia Virus. This is consistent with a requirement for RNA-dependent DNA synthesis in a lytic (non-transforming) cycle of virus growth.

Original language	English (US)
Pages (from-to)	875-880
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	51
Issue number	4
DOIs	https://doi.org/10.1016/0006-291X(73)90008-9
State	Published - Apr 16 1973

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1016/0006-291X(73)90008-9

Find It

Find It at U of M Libraries

Cite this

@article{957e3e4e284840ecb59d32006defa502,

title = "Inhibition of RNA slow viruses by thiosemicarbazones",

abstract = "N-methyl isatin β-thiosemicarbazone (Methisazone) effects comparable reductions in the reverse transcriptase activity and the cytopathic effect of the RNA slow viruses, Visna, Maedi and Progressive Pneumonia Virus. This is consistent with a requirement for RNA-dependent DNA synthesis in a lytic (non-transforming) cycle of virus growth.",

author = "Haase, {Ashley T.} and Warren Levinson",

year = "1973",

month = apr,

day = "16",

doi = "10.1016/0006-291X(73)90008-9",

language = "English (US)",

volume = "51",

pages = "875--880",

journal = "Biochemical and Biophysical Research Communications",

issn = "0006-291X",

publisher = "Academic Press Inc.",

number = "4",

}

TY - JOUR

T1 - Inhibition of RNA slow viruses by thiosemicarbazones

AU - Haase, Ashley T.

AU - Levinson, Warren

PY - 1973/4/16

Y1 - 1973/4/16

N2 - N-methyl isatin β-thiosemicarbazone (Methisazone) effects comparable reductions in the reverse transcriptase activity and the cytopathic effect of the RNA slow viruses, Visna, Maedi and Progressive Pneumonia Virus. This is consistent with a requirement for RNA-dependent DNA synthesis in a lytic (non-transforming) cycle of virus growth.

AB - N-methyl isatin β-thiosemicarbazone (Methisazone) effects comparable reductions in the reverse transcriptase activity and the cytopathic effect of the RNA slow viruses, Visna, Maedi and Progressive Pneumonia Virus. This is consistent with a requirement for RNA-dependent DNA synthesis in a lytic (non-transforming) cycle of virus growth.

UR - http://www.scopus.com/inward/record.url?scp=0015927276&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015927276&partnerID=8YFLogxK

U2 - 10.1016/0006-291X(73)90008-9

DO - 10.1016/0006-291X(73)90008-9

M3 - Article

C2 - 4122206

AN - SCOPUS:0015927276

SN - 0006-291X

VL - 51

SP - 875

EP - 880

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 4

ER -

Inhibition of RNA slow viruses by thiosemicarbazones

Abstract

UN SDGs

Publisher link

Find It

Other files and links

Fingerprint

Cite this