Keyphrases
P13K
100%
Phosphoinositide 3-kinase (PI3K)
100%
AKT Pathway
100%
Targeted Cancer Therapy
100%
Emergent Paradigm
100%
Constitutively Active
75%
Cancer Cells
50%
Phosphatidylinositol 3-kinase/Akt Signaling
50%
Cell Growth
25%
Genetic Basis
25%
Mammalian Target of Rapamycin (mTOR)
25%
Genetic Structure
25%
Molecular Targets
25%
Signaling Pathway
25%
Pathway Inhibitors
25%
Small Molecule Inhibitors
25%
Therapeutic Strategies
25%
Receptor Tyrosine Kinase
25%
Cell Survival
25%
Dysregulation
25%
High Selectivity
25%
Drug Target
25%
Chemical Genetics
25%
Molecular Therapeutics
25%
Major Determinants
25%
Structure-based Drug Design
25%
High Potency
25%
New Inhibitors
25%
Anticancer Therapeutics
25%
Therapeutic Index
25%
Novel Anticancer Agent
25%
Akt Protein
25%
Protein Kinase B Pathway
25%
Phosphatidylinositol 3-kinase/AKT Signaling Pathway
25%
Small Molecule Drugs
25%
Target Receptor
25%
High Bioavailability
25%
Medicine and Dentistry
Molecularly Targeted Therapy
100%
Phosphoinositide 3-Kinase
100%
Akt Signaling
100%
Signal Transduction
42%
Malignant Neoplasm
28%
Cancer Cell
28%
Protein Kinase B
28%
Cell Growth
14%
In Vitro
14%
Cell Survival
14%
Anticarcinogen
14%
Drug Delivery System
14%
Protein Tyrosine Kinase
14%
Bioavailability
14%
Mechanistic Target of Rapamycin
14%
Chemical Genetics
14%
Therapeutic Window
14%
Biochemistry, Genetics and Molecular Biology
Akt Signaling
100%
Phosphoinositide 3-Kinase
100%
Signal Transduction
42%
Small Molecule
28%
Anticancer
28%
Cancer Cell
28%
Protein Kinase B
28%
Drug Targeting
14%
Cell Survival
14%
Chemical Genetics
14%
Receptor Tyrosine Kinase
14%
Cell Growth
14%
Mechanistic Target of Rapamycin
14%
Pharmacology, Toxicology and Pharmaceutical Science
Malignant Neoplasm
100%
Phosphatidylinositol 3 Kinase
100%
Protein Kinase B
28%
Drug Development
14%
Molecular Target
14%
Drug Delivery System
14%
Anticarcinogen
14%
Protein Tyrosine Kinase
14%
Bioavailability
14%
Mammalian Target of Rapamycin
14%
Therapeutic Window
14%