The effect of a novel puromycin analog (I) on the poly U and poly UC directed polyphenylalanine synthesis has been examined. The inhibition of both systems by I corresponded with the inhibitory activities of puromycin. The carbocyclic analog also demonstrated inhibitory activity in three tumor systems grown in tissue culture.
|Original language||English (US)|
|Number of pages||5|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Jan 31 1972|
Bibliographical noteFunding Information:
the U.S. Public Health Service and Grant CAI0979 from the National Cancer