Inhibition of Epstein-Barr Virus by the triterpenoid betulin diphosphate and uvaol

Muhammad Amjad, Robert M Carlson, Pavel Krasutsky, M. Reza Ul Karim

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Betulin, a pentacyclic triterpenoid isolated from the bark of Betula papyrifera. Laboratory synthesized structural analogs were tested for antiviral activities against Epstein-Barr Virus (EBV) by immunofluorescent antiviral assay. Among the several analogs tested, betulin 3,28-diphosphate and uvaol exhibited significant antiviral activities against EBV. The EC50 of betulin 3,28-diphosphate and uvaol was found to be 0.6 μM and 0.7 μM, respectively.

Original languageEnglish (US)
Pages (from-to)1086-1088
Number of pages3
JournalJournal of Microbiology and Biotechnology
Volume14
Issue number5
StatePublished - Oct 1 2004

Keywords

  • Antiviral
  • Epstein-Barr Virus (EBV)
  • Triterpenoid

Fingerprint Dive into the research topics of 'Inhibition of Epstein-Barr Virus by the triterpenoid betulin diphosphate and uvaol'. Together they form a unique fingerprint.

Cite this