Inhibition of Candida albicans by amphotericin B in combination with 5 fluorocytosine

W. H. Beggs, george a sarosi, F. A. Andrews

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Amphotericin B + 5 fluorocytosine combinations were tested for synergism against Candida albicans. Kinetic studies, in which viability was monitored during the early hours of drug exposure in a synthetic medium, gave no indication of either synergism or additive effect. Based on these and earlier studies, it is concluded that demonstration of amphotericin B 5 fluorocytosine synergy is dependent upon methodology.

Original languageEnglish (US)
Pages (from-to)559-562
Number of pages4
JournalRES.COMMUN.CHEM.PATH.PHARMACOL.
Volume8
Issue number3
StatePublished - Dec 1 1974
Externally publishedYes

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