TY - JOUR
T1 - Information and long-term follow-up on a large number of related kidney donors at a single institution
AU - Sutherland, D. E R
AU - Weiland, D.
AU - Chavers, B.
AU - Simmons, R. L.
AU - Ascher, N. L.
AU - Najarian, J. S.
PY - 1985
Y1 - 1985
N2 - From 1963 to 1980, 628 living related kidney donors (LRD) gave kidneys (300 male, 328 female) at a single centre. Surgical complications in 107 donors included wound infections in 14, urine infections in 30, pulmonary events in 65, bleeding in 4, superficial thrombophlebitis in 3, adrenalectomies in 2 and splenectomy in 1. One donor developed a haemolytic uraemic syndrome 1 year after donation. Of 472 donors followed over 1-19 years, 81 have chronic complications, 54 incision pain, 17 incisional hernias, 9 recurrent urine infections and one a neurogenic bladder. Mean blood pressure before donation was 117/73 and in those currently normotensive it is 122/76 mm Hg: 36 of the 472 donors had hypertension before donation; this persisted in 15, while 25 other donors became hypertensive. The mean serum creatinine before donation was 80 ± 9 μmol/l. In 26 donors, urinary protein excretion was 7.1 ± 11.9 mg/24 h. The risk of unilateral nephrectomy is sufficiently low, and the benefits are sufficiently great, to justify LRD transplantation.
AB - From 1963 to 1980, 628 living related kidney donors (LRD) gave kidneys (300 male, 328 female) at a single centre. Surgical complications in 107 donors included wound infections in 14, urine infections in 30, pulmonary events in 65, bleeding in 4, superficial thrombophlebitis in 3, adrenalectomies in 2 and splenectomy in 1. One donor developed a haemolytic uraemic syndrome 1 year after donation. Of 472 donors followed over 1-19 years, 81 have chronic complications, 54 incision pain, 17 incisional hernias, 9 recurrent urine infections and one a neurogenic bladder. Mean blood pressure before donation was 117/73 and in those currently normotensive it is 122/76 mm Hg: 36 of the 472 donors had hypertension before donation; this persisted in 15, while 25 other donors became hypertensive. The mean serum creatinine before donation was 80 ± 9 μmol/l. In 26 donors, urinary protein excretion was 7.1 ± 11.9 mg/24 h. The risk of unilateral nephrectomy is sufficiently low, and the benefits are sufficiently great, to justify LRD transplantation.
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M3 - Article
C2 - 3892326
AN - SCOPUS:0021955337
SN - 0300-2977
VL - 28
SP - 254
EP - 256
JO - Netherlands Journal of Medicine
JF - Netherlands Journal of Medicine
IS - 6
ER -