Influence of surgical strategies on outcome after the Norwood procedure

  • Massimo Griselli
  • , Simon P. McGuirk
  • , Oliver Stümper
  • , Andrew J.B. Clarke
  • , Paul Miller
  • , Rami Dhillon
  • , John G.C. Wright
  • , Joseph V. De Giovanni
  • , David J. Barron
  • , William J. Brawn

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Objective: The study objective was to identify how the evolution of surgical strategies influenced the outcome after the Norwood procedure. Methods: From 1992 to 2004, 367 patients underwent the Norwood procedure (median age, 4 days). Three surgical strategies were identified on the basis of arch reconstruction and source of pulmonary blood flow. The arch was refashioned without extra material in group A (n = 148). The arch was reconstructed with a pulmonary artery homograft patch in groups B (n = 145) and C (n = 74). Pulmonary blood flow was supplied by a modified Blalock-Taussig shunt in groups A and B. Pulmonary blood flow was supplied by a right ventricle to pulmonary artery conduit in group C. Early mortality, actuarial survival, and freedom from arch reintervention or pulmonary artery patch augmentation were analyzed. Results: Early mortality was 28% (n = 102). Actuarial survival was 62% ± 3% at 6 months. Early mortality was lower in group C (15%) than group A (31%) or group B (31%; P <.05). Actuarial survival at 6 months was better in group C (78% ± 5%) than group A (59% ± 5%) or group B (58% ± 4%; P <.05). Fifty-three patients (14%) had arch reintervention. Freedom from arch reintervention was 76% ± 3% at 1 year, with univariable analysis showing no difference among groups A, B, and C (P =.71). One hundred patients (27%) required subsequent pulmonary artery patch augmentation. Freedom from patch augmentation was 61% ± 3% at 1 year, and was lower in group C (3% ± 3%) than group A (80% ± 4%) or group B (72% ± 5%; P <.05). Conclusions: Survival after the Norwood procedure improved after the introduction of a right ventricle to pulmonary artery conduit, but a greater proportion of patients required subsequent pulmonary artery patch augmentation. The type of arch reconstruction did not affect the incidence of arch reintervention.

Original languageEnglish (US)
Pages (from-to)418-426
Number of pages9
JournalJournal of Thoracic and Cardiovascular Surgery
Volume131
Issue number2
DOIs
StatePublished - Feb 2006
Externally publishedYes

Fingerprint

Dive into the research topics of 'Influence of surgical strategies on outcome after the Norwood procedure'. Together they form a unique fingerprint.

Cite this