Influence of involuntary cigarette smoke inhalation on osseointegration: a systematic review and meta-analysis of preclinical studies

F. Javed, S. V. Kellesarian, T. Abduljabbar, A. T. Abduljabbar, Z. Akram, F. Vohra, I. Rahman, G. E. Romanos

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

There are no studies that have systematically reviewed the influence of involuntary cigarette smoke inhalation (ICSI) on the stability of implants. The aim of the present study was to perform a systematic review and meta-analysis of preclinical studies that assessed the influence of involuntary cigarette smoke inhalation ICSI on osseointegration. Indexed databases (PubMed, Google-Scholar, Scopus, EMBASE, and Web of Knowledge) were searched till September 2017. Titles and abstracts of studies identified using the above-described protocol were independently screened by 2 authors. Full-texts of studies judged by title and abstract to be relevant were independently evaluated for the stated eligibility criteria. Nine studies were included. Six studies showed that ICSI compromised bone area contact around implants. In 4 studies, peri-implant bone mineral density was significantly higher in the control group than among subjects exposed to ICSI. For the effects of ICSI on the osseointegration of dental implants, significant differences could be observed for bone-to-implant contact for test subjects in cancellous (Z = −4.08, p < 0.001) and cortical bone (Z = −4.31, p < 0.001) respectively. ICSI may negatively influence osseointegration of dental implants. It is imperative to educate patients about the negative effects of passive smoking on dental and systemic health.

Original languageEnglish (US)
Pages (from-to)764-772
Number of pages9
JournalInternational Journal of Oral and Maxillofacial Surgery
Volume47
Issue number6
DOIs
StatePublished - Jun 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 International Association of Oral and Maxillofacial Surgeons

Keywords

  • alveolar bone loss
  • dental implants
  • osseointegration
  • tobacco smoke pollution

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