Abstract
Interest in corneal wound healing has been fueled largely by the growth in surgical procedures including penetrating keratoplasty and refractive surgery. Recently, we have developed a collagen matrix designed to provide an important in vitro model for corneal wound healing. The matrix for this investigation was a porous collagen matrix composed of type I collagen from bovine corium supplemented with various proteoglycans. Results indicate that soluble factors produced by endothelial cells and insoluble factors produced by stromal fibroblasts influence epithelial layer formation on a collagen sponge.
Original language | English (US) |
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Journal | Annals of Biomedical Engineering |
Volume | 28 |
Issue number | SUPPL. 1 |
State | Published - Dec 1 2000 |
Event | 2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000 |