Bibliographical noteFunding Information:
All incubations were carried out in 25-ml Erlenmeyer flasks containing 2.5 ml of tubular suspension (approximately 12mg protein) in a phosphate buffer (pH 7.4) at 37”. The incubation was started by addition of tubules to the medium which had been equilibrated at 37’ under IOO~,Õ2 for 5 min. Ethanolic solutions of verapamil and D-600 (kindly provided by Knoll Pharmaceutical Co.) were * This investigation was supported by grants from The Health Research Council of the City of New York (U-2326) and the New York Diabetes Association.
Aclinoa,l~~~grttlse ,IIT he authors acknowledge the editorial and typing assistance of Lois Trapp and the technicat assistance of Barbara Hitzemann. This study was supported in part by USPHS Grant DA-00564. H. H. L. is a recipient of an NIMH Research Scientist Career Development Award. K2-DA-70554.