TY - JOUR
T1 - Influence of Age and Sex on Serum Complement Components in Children
AU - Roach, Barbara
AU - Kim, Youngki
AU - Jerome, Elizabeth
AU - Michael, Alfred F.
PY - 1981/10
Y1 - 1981/10
N2 - Concentrations of eight complement components were determined on sera from 419 healthy children (198 boys and 221 girls) aged from 1 to 19 years. A significant correlation between concentration and age for all complement components (C1q, C1s, C4, C3, C5, factor B, properdin, and C[unk] inhibitor) was observed for girls; in the male population, a significant correlation was present only for C1q, C4, C3, C5, and properdin. The presence of a significant relationship to age suggests that this variable must be considered in establishing normal values of serum complement for children.
AB - Concentrations of eight complement components were determined on sera from 419 healthy children (198 boys and 221 girls) aged from 1 to 19 years. A significant correlation between concentration and age for all complement components (C1q, C1s, C4, C3, C5, factor B, properdin, and C[unk] inhibitor) was observed for girls; in the male population, a significant correlation was present only for C1q, C4, C3, C5, and properdin. The presence of a significant relationship to age suggests that this variable must be considered in establishing normal values of serum complement for children.
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U2 - 10.1001/archpedi.1981.02130340030011
DO - 10.1001/archpedi.1981.02130340030011
M3 - Article
C2 - 6975036
AN - SCOPUS:0019455610
SN - 0002-922X
VL - 135
SP - 918
EP - 920
JO - American Journal of Diseases of Children
JF - American Journal of Diseases of Children
IS - 10
ER -