Inflammatory and Immune-Mediated Muscle Disorders

Sian Durward-Akhurst, Stephanie J Valberg

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


A suspicion of inflammatory myopathy in horses arises from clinical history, physical exam findings, hematologic findings, serum biochemistry profile, and bacterial cultures/PCR or serum titers. In horses, inflammatory myopathies are not as well characterized, and it is difficult to clearly discern whether myositis arises as a secondary consequence of an infection, or represents a primary immune-mediated disorder. Nevertheless, for the purposes of stimulating more thought with regard to immune-mediated disorders in horses, this chapter includes inflammatory myopathies linked to the immune response to concurrent infections (e.g., infarctive purpura hemorrhagica (IPH), Streptococcus equi rhabdomyolysis) and those likely triggered by autoimmunity or an aberrant immune response (e.g., immune-mediated myositis in Quarter Horse-related breeds, systemic calcinosis, inflammatory/immune mediated myositis, and sarcoystis myositis).

Original languageEnglish (US)
Title of host publicationEquine Clinical Immunology
Number of pages10
ISBN (Electronic)9781119086512
ISBN (Print)9781118558874
StatePublished - Jan 5 2016

Bibliographical note

Publisher Copyright:
© 2016 by John Wiley & Sons, Inc. All rights reserved.


  • Immune-mediated muscle disorders
  • Immune-mediated muscle disorders
  • Inflammatory muscle disorders
  • IPH
  • Quarter Horse-related breeds
  • Rhabdomyolysis
  • Sarcocystis myositis
  • Streptococcus equi
  • Systemic calcinosis


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