Abstract
Highly purified concanavalin A and other lectins injected in small amounts into the footpads of mice and rats induce an an intense and reproducible edema. Con A is eliminated from the site of injection at a slow rate, which may explain the prolonged nature of the inflammatory response it induces. Some advantages of the use of concanavalin A for the induction of experimental inflammation are discussed.
Original language | English (US) |
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Pages (from-to) | 590-593 |
Number of pages | 4 |
Journal | Proceedings of the Society for Experimental Biology and Medicine |
Volume | 146 |
Issue number | 2 |
DOIs | |
State | Published - Jun 1974 |
Bibliographical note
Funding Information:This investigation was supported by grant AI-10265 from The National Institutes of Health and by Contract NIH-NCI-72-3207 within the Special Virus-Cancer Program of NIH, US Public Health Service.