TY - JOUR
T1 - Infections in Patients with Chronic Kidney Disease
AU - Foley, Robert N.
PY - 2007/9
Y1 - 2007/9
N2 - There has been a notable lack of research activity regarding major infections in patients with advanced chronic kidney disease. To an outsider, this might seem unexpected, because uremia has long been considered a state of immune hyporesponsiveness and rates of major bacterial infection, like septicemia and pneumonia, are known to be orders of magnitude more likely in dialysis populations than in the general population. This article reviews recent literature on the topic, focusing predominantly on the clinical epidemiology of major bacterial infections in dialysis patients, the links between bacterial infections and cardiovascular disease, and randomized trials of interventions designed to prevent these infections.
AB - There has been a notable lack of research activity regarding major infections in patients with advanced chronic kidney disease. To an outsider, this might seem unexpected, because uremia has long been considered a state of immune hyporesponsiveness and rates of major bacterial infection, like septicemia and pneumonia, are known to be orders of magnitude more likely in dialysis populations than in the general population. This article reviews recent literature on the topic, focusing predominantly on the clinical epidemiology of major bacterial infections in dialysis patients, the links between bacterial infections and cardiovascular disease, and randomized trials of interventions designed to prevent these infections.
UR - http://www.scopus.com/inward/record.url?scp=34548387944&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548387944&partnerID=8YFLogxK
U2 - 10.1016/j.idc.2007.06.005
DO - 10.1016/j.idc.2007.06.005
M3 - Review article
C2 - 17826617
AN - SCOPUS:34548387944
SN - 0891-5520
VL - 21
SP - 659
EP - 672
JO - Infectious disease clinics of North America
JF - Infectious disease clinics of North America
IS - 3
ER -
