Infections in Patients with Chronic Kidney Disease

Robert N. Foley

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

There has been a notable lack of research activity regarding major infections in patients with advanced chronic kidney disease. To an outsider, this might seem unexpected, because uremia has long been considered a state of immune hyporesponsiveness and rates of major bacterial infection, like septicemia and pneumonia, are known to be orders of magnitude more likely in dialysis populations than in the general population. This article reviews recent literature on the topic, focusing predominantly on the clinical epidemiology of major bacterial infections in dialysis patients, the links between bacterial infections and cardiovascular disease, and randomized trials of interventions designed to prevent these infections.

Original languageEnglish (US)
Pages (from-to)659-672
Number of pages14
JournalInfectious disease clinics of North America
Volume21
Issue number3
DOIs
StatePublished - Sep 1 2007

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