TY - JOUR
T1 - Infection of gnotobiotic pigs with an Escherichia coli O157:H7 strain associated with an outbreak of hemorrhagic colitis
AU - Francis, D. H.
AU - Collins, J. E.
AU - Duimstra, J. R.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 1986
Y1 - 1986
N2 - Gnotobiotic pigs inoculated with an Escherichia coli O157:H7 strain isolated from a human with hemorrhagic colitis developed anorexia, lethargy, and watery diarrhea. Bacteria diffusely colonized the cecum and colon surfaces and the crypt epithelium. At bacterial attachment sites, microvilli were effaced, and epithelial cells were irregularly shaped, rounded, or detached. Submucosa, lamina propria, and mesentery were markedly edematous and contained many inflammatory cells.
AB - Gnotobiotic pigs inoculated with an Escherichia coli O157:H7 strain isolated from a human with hemorrhagic colitis developed anorexia, lethargy, and watery diarrhea. Bacteria diffusely colonized the cecum and colon surfaces and the crypt epithelium. At bacterial attachment sites, microvilli were effaced, and epithelial cells were irregularly shaped, rounded, or detached. Submucosa, lamina propria, and mesentery were markedly edematous and contained many inflammatory cells.
UR - http://www.scopus.com/inward/record.url?scp=0022612675&partnerID=8YFLogxK
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U2 - 10.1128/iai.51.3.953-956.1986
DO - 10.1128/iai.51.3.953-956.1986
M3 - Article
C2 - 3512443
AN - SCOPUS:0022612675
SN - 0019-9567
VL - 51
SP - 953
EP - 956
JO - Infection and Immunity
JF - Infection and Immunity
IS - 3
ER -
