Induction of xenobiotic enzymes by the map kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)

Keyphrases

• Mitogen-activated Protein Kinase 100%
• Kinase Cascade 100%
• Butylated Hydroxyanisole 100%
• Electrophile Response Element 100%
• Antioxidant Response Element 100%
• Xenobiotic Metabolizing Enzymes 100%
• Xenobiotics 80%
• Tert-butylhydroquinone 80%
• Phenethyl Isothiocyanate (PEITC) 60%
• Phase II Enzymes 60%
• Sulforaphane 60%
• Green Tea Polyphenols 60%
• Phenolic Antioxidants 40%
• Signaling Pathway 40%
• C-Jun N-terminal Kinase 40%
• Extracellular Regulated Protein Kinases 40%
• Protein Kinase 2 40%
• Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) 40%
• Phase II Genes 40%
• Transcription Factor Nrf2 40%
• Gene Activity 20%
• Oxidative Stress 20%
• Transcription Factor 20%
• Phenolic Compounds 20%
• Molecular Mechanism 20%
• Homeostasis 20%
• Complementary DNA (cDNA) 20%
• Antioxidant 20%
• Stress Response 20%
• Cell Survival 20%
• Glutathione 20%
• N-acetylcysteine 20%
• Transcriptional Activation 20%
• Cancer Chemopreventive Agents 20%
• Apoptosis 20%
• Isothiocyanates 20%
• Phytochemicals 20%
• Proline 20%
• Signal Transduction Pathway 20%
• Extracellular Signaling 20%
• Dose Effect 20%
• Inducer 20%
• Cellular Response 20%
• Necrosis 20%
• C-Jun 20%
• Dominant-negative mutant 20%
• Serine-threonine Kinase 20%
• Electrophilic 20%
• Enzyme Induction 20%
• Activating Transcription Factor 2 (ATF2) 20%
• Polyphenol epigallocatechin-3-gallate 20%
• Epigallocatechin-3-gallate 20%
• Induced Stress 20%
• Phosphorylation Reaction 20%
• Luciferase Reporter 20%
• Luciferase Reporter Gene 20%
• Methylated Metabolites 20%
• Free Radical Scavenger 20%
• Basic Leucine Zipper Transcription Factor 20%
• Cellular Defense 20%
• Environmental Harm 20%
• Changes in Gene Expression 20%
• Phenolic Flavonoids 20%
• Food Preservatives 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphotransferase 100%
• Electrophile 100%
• Xenobiotic Agent 100%
• Antioxidant 100%
• Butylated Hydroxyanisole 83%
• Transcription Factor Nrf2 66%
• Phenethyl Isothiocyanate 50%
• Polyphenol 50%
• Sulforaphane 50%
• Mitogen Activated Protein Kinase 1 33%
• Mitogen Activated Protein Kinase 33%
• Epigallocatechin Gallate 33%
• Drug Metabolizing Enzyme 33%
• Luciferase 33%
• Flavonoid 16%
• Enzyme Induction 16%
• Isothiocyanate 16%
• Food Preservative 16%
• Malignant Neoplasm 16%
• Chemopreventive Agents 16%
• Absence 16%
• Cysteine 16%
• Necrosis 16%
• Protein Serine Threonine Kinase 16%
• Glutathione 16%
• Scavenger 16%
• Phytochemical 16%
• Acetic Acid Derivative 16%
• Heterodimer 16%
• Basic Leucine Zipper Transcription Factor 16%
• Transcription Factors 16%
• Proline 16%