Individual Differences in Response to Supervised Exercise Therapy for Peripheral Artery Disease

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Nonresponse to exercise has been extensively examined in young athletes but is seldom reported in studies of aerobic exercise interventions in older adults. This study examined the prevalence of nonresponse and poor response to exercise in functional and quality of life outcomes and response patterns between and among older adults undergoing 12-weeks of supervised exercise therapy for the management of peripheral artery disease (N = 44, mean age 72.3 years, 47.7% female). The prevalence of nonresponse (no change/decline in performance) in walking distance was 31.8%. The prevalence of poor response (lack of a clinically meaningful improvement) was 43.2%. Similar patterns of response were observed in both objective and patient-reported measures of physical function. All participants improved in at least one outcome; only two participants improved in all measured outcomes. Additional research should examine modifiable predictors of response to inform programming and maximize an individual’s potential benefit from exercise therapy.

Original languageEnglish (US)
Pages (from-to)770-784
Number of pages15
JournalWestern journal of nursing research
Issue number8
StatePublished - Dec 17 2020

Bibliographical note

Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Dr. Whipple was a 2015-2017 National Hartford Center of Gerontological Nursing Excellence (NHCGNE) Patricia G. Archbold Scholar. The Patricia G. Archbold Scholar program is supported by a grant to the Gerontological Society of America (GSA)/NHCGNE from the John A. Hartford Foundation. This publication was made possible by a Dissertation Research Grant from the Midwest Nursing Research Society, by the National Institute of Nursing Research (NINR), NIH under a Ruth L. Kirschstein National Research Service Award (F31NR016614, PI Whipple), by the National Institute of Aging (NIA), NIH (T32AG000279, PI Schwartz), and by the National Center for Advancing Translational Sciences (NCATS), NIH (UL1TR002494, PI Blazar). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.


  • exercise
  • older adults
  • peripheral artery disease
  • trainability

PubMed: MeSH publication types

  • Journal Article


Dive into the research topics of 'Individual Differences in Response to Supervised Exercise Therapy for Peripheral Artery Disease'. Together they form a unique fingerprint.

Cite this