Increasing anticarcinoma activity of an anti-erbB2 recombinant immunotoxin by the addition of an anti-EpCAM sFv

Keyphrases

• Anti-carcinoma 100%
• Anti-HER2 Antibody 5%
• Antibody-based 5%
• Athymic nude Mice 5%
• Biological Agents 5%
• Bispecific 50%
• Carcinoma Cell Lines 5%
• Chain Molecules 5%
• Enhanced Antitumor Activity 5%
• Epithelial Cell Adhesion Molecule (EpCAM) 100%
• ErbB2 100%
• Fusion Protein 5%
• Her2neu 5%
• HT-29 5%
• Human Colon Cancer 5%
• Human Epidermal Growth Factor Receptor 2 (HER2) 5%
• Immunotoxin 100%
• In Vitro Study 5%
• In Vivo Activity 5%
• In Vivo Properties 5%
• Recombinant Immunotoxin 100%
• Therapeutic Target 5%
• Toxic Effects 5%
• Tumor 22%
• Tumor Mouse Model 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Antitumor Activity 5%
• Biological Product 10%
• Carcinoma 5%
• Colon Cancer 5%
• Epithelial Cell Adhesion Molecule 100%
• Fusion Protein 5%
• Immunotoxin 100%
• Mouse 10%
• Mouse Model 5%
• Neoplasm 26%
• Nude Mouse 5%
• Toxicity 5%
• Toxin Antibody 5%