Increased Renal Clearance of Amylase in Pancreatitis

Michael D. Levitt, Sidney R. Cooperband

Research output: Contribution to journalEditorialpeer-review

3 Scopus citations


To evaluate the specificity of any new method for diagnosing a disease, the correct diagnosis must first be definitively established by means independent of the test being evaluated. When the test under consideration is for the diagnosis of acute pancreatitis, a problem arises in that an operation is contraindicated, and even when surgery is performed, pathological specimens of the pancreas are seldom obtained. For lack of a better technic, the diagnosis of acute pancreatitis usually depends on demonstration of an elevated serum or urinary amylase level although such elevations are occasionally observed in a variety of other conditions such as….

Original languageEnglish (US)
Pages (from-to)364-365
Number of pages2
JournalNew England Journal of Medicine
Issue number7
StatePublished - Feb 13 1975


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