Increased P Wave Dispersion and Maximum P Wave Duration after Hemodialysis

Ugur K. Tezcan, Basri Amasyali, Ilknur Can, Kudret Aytemir, Sedat Köse, Izzet Yavuz, Hurkan Kursaklioglu, Ersoy Işik, Ertan Demirtaş, Ali Oto

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39 Scopus citations


Background: Atrial fibrillation is a frequent arrhythmia in patients undergoing hemodialysis. The consequences of hemodialysis on P wave durations and P wave dispersion have not been fully understood. The objective of this study was to study the effect of dialysis on P wave maximum (Pmax), P wave minimum (Pmin), and P wave dispersion (Pd). Methods: We studied Pmax, Pmin, and Pd in 32 patients (17 men and 15 women, mean age 54 ± 18 years) with chronic renal failure undergoing hemodialysis. The difference between maximum and minimum P wave duration was calculated and defined as P wave dispersion (P d = Pmax - Pmin). Results: There was a significant increase in Pmax at the end of dialysis compared to the beginning (98 ± 13 ms vs. 125 ± 12 ms, P < 0.001). P min did not show any significant change (71 ± 11 ms vs. 73 ± 10 ms, P = 0.42). Pd was significantly increased at the end of dialysis (27 ± 9 ms vs. 52 ± 11 ms, P < 0.001). There was a negative correlation between serum potassium, magnesium, phosphate, blood urea nitrogen, and creatinin at the end of dialysis and Pmax and P d respectively (P < 0.05). A weak positive correlation was found between serum calcium, bicarbonate at the end of dialysis and Pmax and Pd (P < 0.05). Conclusion: Hemodialysis ends with significant increase in P wave maximum duration and P wave dispersion, which might be responsible for the increased occurrence of atrial fibrillation in these groups of patients.

Original languageEnglish (US)
Pages (from-to)34-38
Number of pages5
JournalAnnals of Noninvasive Electrocardiology
Issue number1
StatePublished - Jan 2004


  • Atrial fibrillation
  • Hemodialysis
  • P wave dispersion


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