In vivo site-directed mutagenesis of the factor IX gene by chimetic RND/DNA oligonucleotides

Keyphrases

• Site-directed mutagenesis 100%
• DNA Oligonucleotides 100%
• Factor 9 100%
• Hepatocytes 66%
• RNA-DNA 66%
• Cell Culture 33%
• Coagulation 33%
• Intravenous Injection 33%
• Hepatic Genes 33%
• In Situ 33%
• Viral Vectors 33%
• Oligonucleotides 33%
• Dose Effect 33%
• Mutated Genes 33%
• Single Base 33%
• Activated Partial Thromboplastin Time (aPTT) 33%
• Chimeric RNA 33%
• Coagulant Activity 33%
• Sequence mutation 33%
• Gene Repair 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Site-Directed Mutagenesis 100%
• Blood Clotting Factor 9 100%
• Oligonucleotide 100%
• Cell Culture 25%
• Viral Vector 25%
• Coagulating Agent 25%
• Base 25%
• Thromboplastin 25%

Immunology and Microbiology

• Site Directed Mutagenesis 100%
• DNA RNA Hybridization 100%
• Viral Vector 50%
• Cell Culture 50%
• Thromboplastin 50%