In vitro assessment of long-term reliability of low-cost μηCoG arrays

Kay Palopoli-Trojani; Virginia Woods; Chia Han Chiang; Michael Trumpis; Jonathan Viventi

doi:10.1109/EMBC.2016.7591728

In vitro assessment of long-term reliability of low-cost μηCoG arrays

Kay Palopoli-Trojani, Virginia Woods, Chia Han Chiang, Michael Trumpis, Jonathan Viventi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

12 Scopus citations

Abstract

Micro-electrocorticographic (μηΟΟ) electrode arrays provide a minimally invasive, high-resolution neural interface with broad cortical coverage. Previously, we fabricated μηCoG arrays at a lower cost than commercially available devices using low-cost industrial processes [1], [2]. Here, we report the in vitro electrical performance of five μηCoG designs undergoing an accelerated aging protocol. The impedance and yield of the μηCoG arrays were tracked over time. The equivalent lifetime at 37°C depended on the manufacturer and material stack-up, and ranged between 30 and greater than 760 days (ongoing). The main failure modes of these devices were delamination at the site of the electrode contact and broken traces due to metal dissolution. Based on these in vitro results, we offer several recommendations for μηCoG designs suitable for chronic implantation.

Original language	English (US)
Title of host publication	2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	4503-4506
Number of pages	4
ISBN (Electronic)	9781457702204
DOIs	https://doi.org/10.1109/EMBC.2016.7591728
State	Published - Oct 13 2016
Externally published	Yes
Event	38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States Duration: Aug 16 2016 → Aug 20 2016

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume	2016-October
ISSN (Print)	1557-170X

Other

Other	38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Country/Territory	United States
City	Orlando
Period	8/16/16 → 8/20/16

Bibliographical note

Publisher Copyright:
© 2016 IEEE.

Publisher link

10.1109/EMBC.2016.7591728

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Palopoli-Trojani, K., Woods, V., Chiang, C. H., Trumpis, M., & Viventi, J. (2016). In vitro assessment of long-term reliability of low-cost μηCoG arrays. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 (pp. 4503-4506). Article 7591728 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2016-October). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2016.7591728

In vitro assessment of long-term reliability of low-cost μηCoG arrays. / Palopoli-Trojani, Kay; Woods, Virginia; Chiang, Chia Han et al.
2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. 4503-4506 7591728 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2016-October).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Palopoli-Trojani, K, Woods, V, Chiang, CH, Trumpis, M & Viventi, J 2016, In vitro assessment of long-term reliability of low-cost μηCoG arrays. in 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016., 7591728, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2016-October, Institute of Electrical and Electronics Engineers Inc., pp. 4503-4506, 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016, Orlando, United States, 8/16/16. https://doi.org/10.1109/EMBC.2016.7591728

Palopoli-Trojani K, Woods V, Chiang CH, Trumpis M, Viventi J. In vitro assessment of long-term reliability of low-cost μηCoG arrays. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc. 2016. p. 4503-4506. 7591728. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2016.7591728

Palopoli-Trojani, Kay ; Woods, Virginia ; Chiang, Chia Han et al. / In vitro assessment of long-term reliability of low-cost μηCoG arrays. 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., 2016. pp. 4503-4506 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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abstract = "Micro-electrocorticographic (μηΟΟ) electrode arrays provide a minimally invasive, high-resolution neural interface with broad cortical coverage. Previously, we fabricated μηCoG arrays at a lower cost than commercially available devices using low-cost industrial processes [1], [2]. Here, we report the in vitro electrical performance of five μηCoG designs undergoing an accelerated aging protocol. The impedance and yield of the μηCoG arrays were tracked over time. The equivalent lifetime at 37°C depended on the manufacturer and material stack-up, and ranged between 30 and greater than 760 days (ongoing). The main failure modes of these devices were delamination at the site of the electrode contact and broken traces due to metal dissolution. Based on these in vitro results, we offer several recommendations for μηCoG designs suitable for chronic implantation.",

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In vitro assessment of long-term reliability of low-cost μηCoG arrays

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