In vitro and in vivo tests of hydroxyapatite-gleatin nanocomposites for bone regeneration: A preliminary report

C. C. Ko, Y. L. Wu, W. H. Douglas, R. Narayanan, W. S. Hu

Research output: Contribution to journalConference articlepeer-review

6 Scopus citations

Abstract

Hydroxyapatite-gelatin (HAP-GEL) nanocomposites, for bone regeneration, were analyze using a biomeimetic process. The HAP-GEL rods were implanted into the proximal femur of Sprague-Dawley rats to assess the cell proliferation. It was observed that after fours of attachment, most cells appeared round in all discs. It was found that higher gelatin content lead to higher cell growth. The results show that HAP-GEL supports the attachment, proliferation and differentiation of osteoblasts.

Original languageEnglish (US)
Pages (from-to)255-260
Number of pages6
JournalMaterials Research Society Symposium - Proceedings
Volume823
StatePublished - Oct 26 2004
EventBiological and Bioinspired Materials and Devices - San Francisco, CA, United States
Duration: Apr 13 2004Apr 16 2004

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