TY - JOUR
T1 - In-silico interaction of RNA silencing suppressors of velvet bean severe mosaic virus with DICER domains
AU - Jangid, Aruna
AU - Chandel, Vanita
AU - Jesse, Michael I.
AU - Srivastava, Ashish
AU - Rishi, Narayan
N1 - Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/11/8
Y1 - 2017/11/8
N2 - Velvet bean severe mosaic virus (VbSMV), a bipartite begomovirus causes severe mosaic, downward curling of the leaves, stunting of the plants in velvet beans (Mucuna pruriens). VbSMV contains two potential viral suppressors of RNA silencing, AC2 and AV2. To understand the mechanism of suppression of host defence and interaction of VSRs with host DICER, the in-silico interaction study was performed. Evidence of interaction of the AC2 protein with the type III restriction enzyme domain, helicase superfamily c-terminal domain and transcription repair coupling factor, whereas AV2 protein with ribonuclease III C terminal domain, ERCC4-related helicase domain, ribonuclease III domain, Dicer dimerization domain, type III restriction enzyme RES subunit and transcription repair coupling factor were found. This is the first in-silico evidence of interaction of any begomoviral VSRs (viral suppressors of RNA silencing) with Dicer of host.
AB - Velvet bean severe mosaic virus (VbSMV), a bipartite begomovirus causes severe mosaic, downward curling of the leaves, stunting of the plants in velvet beans (Mucuna pruriens). VbSMV contains two potential viral suppressors of RNA silencing, AC2 and AV2. To understand the mechanism of suppression of host defence and interaction of VSRs with host DICER, the in-silico interaction study was performed. Evidence of interaction of the AC2 protein with the type III restriction enzyme domain, helicase superfamily c-terminal domain and transcription repair coupling factor, whereas AV2 protein with ribonuclease III C terminal domain, ERCC4-related helicase domain, ribonuclease III domain, Dicer dimerization domain, type III restriction enzyme RES subunit and transcription repair coupling factor were found. This is the first in-silico evidence of interaction of any begomoviral VSRs (viral suppressors of RNA silencing) with Dicer of host.
KW - DICER
KW - In-silico
KW - RNA silencing suppressor
KW - velvet bean
UR - https://www.scopus.com/pages/publications/85034237728
UR - https://www.scopus.com/inward/citedby.url?scp=85034237728&partnerID=8YFLogxK
U2 - 10.1080/03235408.2017.1402533
DO - 10.1080/03235408.2017.1402533
M3 - Article
AN - SCOPUS:85034237728
SN - 0323-5408
VL - 50
SP - 900
EP - 908
JO - Archives of Phytopathology and Plant Protection
JF - Archives of Phytopathology and Plant Protection
IS - 17-18
ER -
