Improving infrastructure for pathway prediction.

Junfeng Gao; Lynda B M Ellis

Improving infrastructure for pathway prediction.

Junfeng Gao
, Lynda B M Ellis

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The UM-BBD Pathway Prediction System (UM-PPS, http://umbbd.msi.umn.edu/predict/) predicts microbial catabolism of organic compounds. We improved UM-PPS infrastructure to improve pathway prediction results. We added the ability to allow relative reasoning and variable aerobic likelihood. One relative reasoning entry decreased choices 75% with no loss of sensitivity. Variable aerobic likelihood gives more accurate likelihood for rules triggered by substrates with certain chemical structures. Predictions are improved.

Original language	English (US)
Number of pages	1
Journal	AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
State	Published - Dec 1 2008

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title = "Improving infrastructure for pathway prediction.",

abstract = "The UM-BBD Pathway Prediction System (UM-PPS, http://umbbd.msi.umn.edu/predict/) predicts microbial catabolism of organic compounds. We improved UM-PPS infrastructure to improve pathway prediction results. We added the ability to allow relative reasoning and variable aerobic likelihood. One relative reasoning entry decreased choices 75\% with no loss of sensitivity. Variable aerobic likelihood gives more accurate likelihood for rules triggered by substrates with certain chemical structures. Predictions are improved.",

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AB - The UM-BBD Pathway Prediction System (UM-PPS, http://umbbd.msi.umn.edu/predict/) predicts microbial catabolism of organic compounds. We improved UM-PPS infrastructure to improve pathway prediction results. We added the ability to allow relative reasoning and variable aerobic likelihood. One relative reasoning entry decreased choices 75% with no loss of sensitivity. Variable aerobic likelihood gives more accurate likelihood for rules triggered by substrates with certain chemical structures. Predictions are improved.

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SN - 1559-4076

JO - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

JF - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

ER -

Improving infrastructure for pathway prediction.

Abstract

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