Improving Global Outcomes

Kai Uwe Eckardt, Bert L Kasiske

Research output: Contribution to journalReview articlepeer-review

85 Scopus citations


Kidney Disease: Improving Global Outcomes (KDIGO) is an independent organization with the mission to improve care and outcomes of patients with kidney disease worldwide through the development and coordination of clinical practice guidelines. KDIGO has established firm links with other organizations that have previously produced clinical practice guidelines in the field of kidney disease. The first three KDIGO guidelinestreatment of hepatitis C, management of bone and mineral disease, and care of kidney transplant recipientshave been finalized and the next threeacute kidney injury, management of glomerulonephritis, and management of blood pressure in chronic kidney diseaseare under development. The ultimate goal is to cover most major aspects of care for patients with kidney disease. Corner stones of KDIGO's guideline development process are independent, multidisciplinary, international work groups, close collaboration with professional methodology experts who perform systematic evidence reviews, and open public review of each guideline. Grades of Recommendation Assessment, Development, and Evaluation (GRADE) methodology is applied for grading the quality of evidence and strength of recommendations. International conferences organized by KDIGO support the coordination of guideline development, assess the suitability of guideline topics and help to establish global consensus on definitions and policies.

Original languageEnglish (US)
Pages (from-to)650-657
Number of pages8
JournalNature Reviews Nephrology
Issue number11
StatePublished - Nov 1 2009


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