Improvement of depression and parkinsonism during ECT: A case study

Maurice Dysken, Henry M. Evans, Carlyle H. Chan, John M. Davis

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Improvement in signs of parkinsonism and symptoms of depression was observed in a patient with Parkinson's disease who underwent a course of ECT for depression. Empirically this patient was observed by a blind rater to show a pattern of improvement in parkinsonian signs similar to that observed in parkinsonian patients treated with L-dopa. The time course of improvement of this patient's depression was also seen to parallel improvement in his Parkinson's disease. These results are consistent with the hypothesis that ECT increases catecholamine synthesis and more specifically would be evidence that ECT improves depression by increasing norepinephrine synthesis.

Original languageEnglish (US)
Pages (from-to)81-86
Number of pages6
JournalNeuropsychobiology
Volume2
Issue number2-3
DOIs
StatePublished - Jan 1 1976

Keywords

  • Depression
  • ECT
  • Parkinsonism

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