Perfusion cardiac MRI (CMR) is a radiation-free and noninvasive imaging tool which has gained increasing interest for the diagnosis of coronary artery disease. However, resolution and coverage are limited in perfusion CMR due to the necessity of single snap-shot imaging during the first-pass of a contrast agent. Simultaneous multi-slice (SMS) imaging has the potential for high acceleration rates with minimal signal-to-noise ratio (SNR) loss. However, its utility in CMR has been limited to moderate acceleration factors due to residual leakage artifacts from the extra-cardiac tissue such as the chest and the back. Outer volume suppression (OVS) with leakage-blocking reconstruction has been used to enable higher acceleration rates in perfusion CMR, but suffers from higher noise amplification. In this study, we sought to augment OVS-SMS/MB imaging with a regularized leakage-blocking reconstruction algorithm to improve image quality. Results from highly-accelerated perfusion CMR show that the method improves upon SMS-SPIRiT in terms of leakage reduction and split slice (ss)-GRAPPA in terms of noise mitigation.
|Original language||English (US)|
|Title of host publication||ISBI 2020 - 2020 IEEE International Symposium on Biomedical Imaging|
|Publisher||IEEE Computer Society|
|Number of pages||4|
|State||Published - Apr 2020|
|Event||17th IEEE International Symposium on Biomedical Imaging, ISBI 2020 - Iowa City, United States|
Duration: Apr 3 2020 → Apr 7 2020
|Name||Proceedings - International Symposium on Biomedical Imaging|
|Conference||17th IEEE International Symposium on Biomedical Imaging, ISBI 2020|
|Period||4/3/20 → 4/7/20|
Bibliographical noteFunding Information:
This work was partially supported by NIH R00HL111410, NIH P41EB027061 and NSF CAREER CCF-1651825. Ö.B. Demirel was partially supported by an AHA Predoctoral Fellowship.
© 2020 IEEE.
- Magnetic resonance imaging
- accelerated MRI
- myocardial perfusion
- outer volume suppression
- parallel imaging
- simultaneous multi-slice imaging