Improved reproducibility of CT calcium score using blind deconvolution

Yingnan Song; Ammar Hoori; Hao Wu; Sadeer Al-Kindi; Jared Christian Durieux; James G. Terry; David R. Jacobs; Jamal S. Rana; John Jeffrey Carr; David L. Wilson

doi:10.1117/12.2580484

Improved reproducibility of CT calcium score using blind deconvolution

Yingnan Song, Ammar Hoori, Hao Wu, Sadeer Al-Kindi, Jared Christian Durieux, James G. Terry, David R. Jacobs, Jamal S. Rana, John Jeffrey Carr, David L. Wilson

Epidemiology & Community Health

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Our ultimate goal is to predict adverse cardiovascular events from CT calcium score exams using radiomics. Unlike the traditional whole heart Agatston score, our approach analyzes individual calcifications, creating a challenge for accurate/reproducible assessments. Optional preprocessing consisted of 3D blind deconvolution optimized on masked sharp structures, giving PSFs similar to measured ones, followed by noise reduction. In our experiment, we found that blind deconvolution improves the accuracy and reproducibility of CT calcium score evaluation. It is beneficial to use this to predict adverse cardiovascular event since it provides a robust and accurate evaluation of clinically relevant and pre-clinical calcifications. We conclude that for archived images where PSFs are unavailable, 3D blind deconvolution is a useful preprocessing step for improved radiomics assessments of CT-calcium-score images.

Original language	English (US)
Title of host publication	Medical Imaging 2021
Subtitle of host publication	Biomedical Applications in Molecular, Structural, and Functional Imaging
Editors	Barjor S. Gimi, Andrzej Krol
Publisher	SPIE
ISBN (Electronic)	9781510640290
DOIs	https://doi.org/10.1117/12.2580484
State	Published - 2021
Event	Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging - Virtual, Online, United States Duration: Feb 15 2021 → Feb 19 2021

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	11600
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging
Country	United States
City	Virtual, Online
Period	2/15/21 → 2/19/21

Bibliographical note

Funding Information:
The Coronary Artery Risk Development in Young Adults Study (CARDIA) is supported by contracts HHSN268201800003I, HHSN268201800004I, HHSN268201800005I, HHSN268201800006I, and HHSN-268201800007I from the National Heart, Lung, and Blood Institute (NHLBI). Collection of CT data was in part supported by RO1 HL098445 (to JJC). Hao Wu was supported by the Interdisciplinary Biomedical Imaging Training Program, NIH T32EB007509 administered by the Department of Biomedical Engineering, Case Western Reserve University. This report is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

Keywords

Calcium score
Coronary artery calcification
Deconvolution

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Song, Y., Hoori, A., Wu, H., Al-Kindi, S., Durieux, J. C., Terry, J. G., Jacobs, D. R., Rana, J. S., Carr, J. J., & Wilson, D. L. (2021). Improved reproducibility of CT calcium score using blind deconvolution. In B. S. Gimi, & A. Krol (Eds.), Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging [116000V] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11600). SPIE. https://doi.org/10.1117/12.2580484

Improved reproducibility of CT calcium score using blind deconvolution. / Song, Yingnan; Hoori, Ammar; Wu, Hao; Al-Kindi, Sadeer; Durieux, Jared Christian; Terry, James G.; Jacobs, David R.; Rana, Jamal S.; Carr, John Jeffrey; Wilson, David L.

Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging. ed. / Barjor S. Gimi; Andrzej Krol. SPIE, 2021. 116000V (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11600).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Song, Y, Hoori, A, Wu, H, Al-Kindi, S, Durieux, JC, Terry, JG, Jacobs, DR, Rana, JS, Carr, JJ & Wilson, DL 2021, Improved reproducibility of CT calcium score using blind deconvolution. in BS Gimi & A Krol (eds), Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging., 116000V, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 11600, SPIE, Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging, Virtual, Online, United States, 2/15/21. https://doi.org/10.1117/12.2580484

Song Y, Hoori A, Wu H, Al-Kindi S, Durieux JC, Terry JG et al. Improved reproducibility of CT calcium score using blind deconvolution. In Gimi BS, Krol A, editors, Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging. SPIE. 2021. 116000V. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2580484

Song, Yingnan ; Hoori, Ammar ; Wu, Hao ; Al-Kindi, Sadeer ; Durieux, Jared Christian ; Terry, James G. ; Jacobs, David R. ; Rana, Jamal S. ; Carr, John Jeffrey ; Wilson, David L. / Improved reproducibility of CT calcium score using blind deconvolution. Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging. editor / Barjor S. Gimi ; Andrzej Krol. SPIE, 2021. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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title = "Improved reproducibility of CT calcium score using blind deconvolution",

abstract = "Our ultimate goal is to predict adverse cardiovascular events from CT calcium score exams using radiomics. Unlike the traditional whole heart Agatston score, our approach analyzes individual calcifications, creating a challenge for accurate/reproducible assessments. Optional preprocessing consisted of 3D blind deconvolution optimized on masked sharp structures, giving PSFs similar to measured ones, followed by noise reduction. In our experiment, we found that blind deconvolution improves the accuracy and reproducibility of CT calcium score evaluation. It is beneficial to use this to predict adverse cardiovascular event since it provides a robust and accurate evaluation of clinically relevant and pre-clinical calcifications. We conclude that for archived images where PSFs are unavailable, 3D blind deconvolution is a useful preprocessing step for improved radiomics assessments of CT-calcium-score images. ",

keywords = "Calcium score, Coronary artery calcification, Deconvolution",

author = "Yingnan Song and Ammar Hoori and Hao Wu and Sadeer Al-Kindi and Durieux, {Jared Christian} and Terry, {James G.} and Jacobs, {David R.} and Rana, {Jamal S.} and Carr, {John Jeffrey} and Wilson, {David L.}",

note = "Funding Information: The Coronary Artery Risk Development in Young Adults Study (CARDIA) is supported by contracts HHSN268201800003I, HHSN268201800004I, HHSN268201800005I, HHSN268201800006I, and HHSN-268201800007I from the National Heart, Lung, and Blood Institute (NHLBI). Collection of CT data was in part supported by RO1 HL098445 (to JJC). Hao Wu was supported by the Interdisciplinary Biomedical Imaging Training Program, NIH T32EB007509 administered by the Department of Biomedical Engineering, Case Western Reserve University. This report is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging ; Conference date: 15-02-2021 Through 19-02-2021",

year = "2021",

doi = "10.1117/12.2580484",

language = "English (US)",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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AU - Hoori, Ammar

AU - Wu, Hao

AU - Al-Kindi, Sadeer

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AU - Terry, James G.

AU - Jacobs, David R.

AU - Rana, Jamal S.

AU - Carr, John Jeffrey

AU - Wilson, David L.

N1 - Funding Information: The Coronary Artery Risk Development in Young Adults Study (CARDIA) is supported by contracts HHSN268201800003I, HHSN268201800004I, HHSN268201800005I, HHSN268201800006I, and HHSN-268201800007I from the National Heart, Lung, and Blood Institute (NHLBI). Collection of CT data was in part supported by RO1 HL098445 (to JJC). Hao Wu was supported by the Interdisciplinary Biomedical Imaging Training Program, NIH T32EB007509 administered by the Department of Biomedical Engineering, Case Western Reserve University. This report is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Publisher Copyright: © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

PY - 2021

Y1 - 2021

N2 - Our ultimate goal is to predict adverse cardiovascular events from CT calcium score exams using radiomics. Unlike the traditional whole heart Agatston score, our approach analyzes individual calcifications, creating a challenge for accurate/reproducible assessments. Optional preprocessing consisted of 3D blind deconvolution optimized on masked sharp structures, giving PSFs similar to measured ones, followed by noise reduction. In our experiment, we found that blind deconvolution improves the accuracy and reproducibility of CT calcium score evaluation. It is beneficial to use this to predict adverse cardiovascular event since it provides a robust and accurate evaluation of clinically relevant and pre-clinical calcifications. We conclude that for archived images where PSFs are unavailable, 3D blind deconvolution is a useful preprocessing step for improved radiomics assessments of CT-calcium-score images.

AB - Our ultimate goal is to predict adverse cardiovascular events from CT calcium score exams using radiomics. Unlike the traditional whole heart Agatston score, our approach analyzes individual calcifications, creating a challenge for accurate/reproducible assessments. Optional preprocessing consisted of 3D blind deconvolution optimized on masked sharp structures, giving PSFs similar to measured ones, followed by noise reduction. In our experiment, we found that blind deconvolution improves the accuracy and reproducibility of CT calcium score evaluation. It is beneficial to use this to predict adverse cardiovascular event since it provides a robust and accurate evaluation of clinically relevant and pre-clinical calcifications. We conclude that for archived images where PSFs are unavailable, 3D blind deconvolution is a useful preprocessing step for improved radiomics assessments of CT-calcium-score images.

KW - Calcium score

KW - Coronary artery calcification

KW - Deconvolution

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ER -

Improved reproducibility of CT calcium score using blind deconvolution

Abstract

Publication series

Conference

Bibliographical note

Keywords

Access

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