Abstract
Our ultimate goal is to predict adverse cardiovascular events from CT calcium score exams using radiomics. Unlike the traditional whole heart Agatston score, our approach analyzes individual calcifications, creating a challenge for accurate/reproducible assessments. Optional preprocessing consisted of 3D blind deconvolution optimized on masked sharp structures, giving PSFs similar to measured ones, followed by noise reduction. In our experiment, we found that blind deconvolution improves the accuracy and reproducibility of CT calcium score evaluation. It is beneficial to use this to predict adverse cardiovascular event since it provides a robust and accurate evaluation of clinically relevant and pre-clinical calcifications. We conclude that for archived images where PSFs are unavailable, 3D blind deconvolution is a useful preprocessing step for improved radiomics assessments of CT-calcium-score images.
Original language | English (US) |
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Title of host publication | Medical Imaging 2021 |
Subtitle of host publication | Biomedical Applications in Molecular, Structural, and Functional Imaging |
Editors | Barjor S. Gimi, Andrzej Krol |
Publisher | SPIE |
ISBN (Electronic) | 9781510640290 |
DOIs | |
State | Published - 2021 |
Event | Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging - Virtual, Online, United States Duration: Feb 15 2021 → Feb 19 2021 |
Publication series
Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
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Volume | 11600 |
ISSN (Print) | 1605-7422 |
Conference
Conference | Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging |
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Country/Territory | United States |
City | Virtual, Online |
Period | 2/15/21 → 2/19/21 |
Bibliographical note
Publisher Copyright:© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.
Keywords
- Calcium score
- Coronary artery calcification
- Deconvolution