Improved and practical synthesis of 2-deoxy-l-ribose by hypophosphite-mediated deoxygenation

Li Li Chen; Xun Ming; Jun Da Cen

doi:10.1080/00397911.2010.520402

Improved and practical synthesis of 2-deoxy-l-ribose by hypophosphite-mediated deoxygenation

Li Li Chen, Xun Ming, Jun Da Cen

Masonic Cancer Center

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

An improved and practical route for a large-scale synthesis of 2-deoxy-L-ribose starting from L-arabinose has been developed. This is the first reported synthesis of 2-deoxy-L-ribose in which deoxygenation has been mediated by hypophosphite reagents instead of by organotin reagents.

Original language	English (US)
Pages (from-to)	1-7
Number of pages	7
Journal	Synthetic Communications
Volume	42
Issue number	1
DOIs	https://doi.org/10.1080/00397911.2010.520402
State	Published - Jan 2012

Keywords

2-Deoxy-L-ribose
N-ethylpiperidine hypophosphite
hypophosphite-mediated deoxygenation
hypophosphorous acid
synthesis

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10.1080/00397911.2010.520402

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abstract = "An improved and practical route for a large-scale synthesis of 2-deoxy-L-ribose starting from L-arabinose has been developed. This is the first reported synthesis of 2-deoxy-L-ribose in which deoxygenation has been mediated by hypophosphite reagents instead of by organotin reagents.",

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KW - N-ethylpiperidine hypophosphite

KW - hypophosphite-mediated deoxygenation

KW - hypophosphorous acid

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Improved and practical synthesis of 2-deoxy-l-ribose by hypophosphite-mediated deoxygenation

Abstract

Keywords

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