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Improved and practical synthesis of 2-deoxy-l-ribose by hypophosphite-mediated deoxygenation

  • Li Li Chen
  • , Xun Ming
  • , Jun Da Cen

Research output: Contribution to journal › Article › peer-review

Abstract

An improved and practical route for a large-scale synthesis of 2-deoxy-L-ribose starting from L-arabinose has been developed. This is the first reported synthesis of 2-deoxy-L-ribose in which deoxygenation has been mediated by hypophosphite reagents instead of by organotin reagents.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalSynthetic Communications
Volume42
Issue number1
DOIs
StatePublished - Jan 2012

Keywords

  • 2-Deoxy-L-ribose
  • N-ethylpiperidine hypophosphite
  • hypophosphite-mediated deoxygenation
  • hypophosphorous acid
  • synthesis

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