Improved and practical synthesis of 2-deoxy-l-ribose by hypophosphite-mediated deoxygenation

Li Li Chen, Xun Ming, Jun Da Cen

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

An improved and practical route for a large-scale synthesis of 2-deoxy-L-ribose starting from L-arabinose has been developed. This is the first reported synthesis of 2-deoxy-L-ribose in which deoxygenation has been mediated by hypophosphite reagents instead of by organotin reagents.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalSynthetic Communications
Volume42
Issue number1
DOIs
StatePublished - Jan 2012

Bibliographical note

Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.

Keywords

  • 2-Deoxy-L-ribose
  • N-ethylpiperidine hypophosphite
  • hypophosphite-mediated deoxygenation
  • hypophosphorous acid
  • synthesis

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