Abstract
The cardiovascular cell therapy network was developed by the National Heart, Lung and Blood Institute to design and conduct clinical trials to advance the field of cardiovascular (CV) cell-based therapy. The Cardiovascular Cell Therapy Network successfully completed three clinical trials involving approximately 300 subjects across five centers and six satellites. Although the concept of a network within clinical trials research is not new, the knowledge gained in the implementation of such large-scale trials, particularly in novel therapeutic areas such as cell therapy is not often detailed in the literature. The purpose of this communication is to summarize key factors in achieving network goals and share the knowledge gained to promote success in future cardiovascular disease cell therapy trials and networks.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1495-1502 |
| Number of pages | 8 |
| Journal | Expert review of cardiovascular therapy |
| Volume | 11 |
| Issue number | 11 |
| DOIs | |
| State | Published - 2013 |
| Externally published | Yes |
Bibliographical note
Funding Information:The authors were partially supported through funding received by the CCTRN provided by the NHLBI under cooperative agreement 5 UM1 HL087318-07. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
Keywords
- FOCUS
- LateTIME
- TIME
- acute myocardial infarction
- cardiovascular cell therapy network
- cardiovascular disease
- heart failure
- network
- stem cell therapy
