TY - JOUR
T1 - Impact of the AYA HOPE comorbidity index on assessing health care service needs and health status among adolescents and young adults with cancer
AU - Wu, Xiao Cheng
AU - Prasad, Pinki K.
AU - Landry, Ian
AU - Harlan, Linda C.
AU - Parsons, Helen M.
AU - Lynch, Charles F.
AU - Smith, Ashley W.
AU - Hamilton, Ann S.
AU - Keegan, Theresa H.M.
AU - Schwartz, Stephen M.
AU - Shellenberger, Martha
AU - Janes, Tiffany
AU - West, Michele M.
AU - Somers, Lori A.
AU - Kato, Ikuko
AU - Bankowski, Ann
AU - Stock, Marjorie
AU - Cress, Rosemary
AU - Agha, Gretchen
AU - Cruz, Mark
AU - Chen, Vivien
AU - Allen, Laura
AU - Loya, Zinnia
AU - Shelton-Herendeen, Lisa
AU - Zelaya, Jennifer
AU - Trinidad, Urduja
AU - Keel, Gretchen
AU - Eisenstein, Jana
AU - Potosky, Arnold
AU - Bellizzi, Keith
AU - Albritton, Karen
AU - Link, Michael
AU - Friedman, Debra
AU - Zebrack, Brad
N1 - Publisher Copyright:
© 2015 American Association for Cancer Research.
PY - 2015/12
Y1 - 2015/12
N2 - Background: Existing comorbidity indices were not developed for adolescent and young adults (AYA) 15 to 39 years of age. The aim of this study was to assess impact of comorbidities on health care service needs and health status among AYA cancer survivors using the newly developed AYA HOPE comorbidity index in comparison with the existing indices. Methods: Data on comorbid conditions were obtained from medical records and service needs and health status were from a survey of AYA cancer survivors. Prevalence of comorbidities was based on the AYA HOPE index. Charlson and NCI indices were compared. Multivariable logistic regression was used. Results: Of the 485 patients, 14.6% had ≥2 comorbidities based on the AYA HOPE Index. Prevalence of mental illness and obesity/overweight, which were not included in existing indices, were 8.2% and 5.8%, respectively. Prevalence of cardiovascular, endocrine, gastrointestinal, and neurologic conditions were higher with the AYA HOPE Index than the other two indices. Forty percent of AYA patients reported service needs, particularly for mental health services (25.2%) and support groups (17.7%). Having ≥2 comorbidities on the AYA index was associated with higher mental health service needs [OR, 2.05; 95% confidence interval (CI), 1.10-3.82] adjusting for demographic and clinical factors. Comorbidities were associated with fair/poor selfreported health status. Conclusion: The AYA HOPE Index is a more comprehensive comorbidity index for AYA cancer patients than existing indices, and the number of comorbidities is associated with service needs and health status. Impact: The AYA HOPE index could identify patients' additional service needs early in therapy. Cancer Epidemiol Biomarkers Prev; 24(12); 1844-9.
AB - Background: Existing comorbidity indices were not developed for adolescent and young adults (AYA) 15 to 39 years of age. The aim of this study was to assess impact of comorbidities on health care service needs and health status among AYA cancer survivors using the newly developed AYA HOPE comorbidity index in comparison with the existing indices. Methods: Data on comorbid conditions were obtained from medical records and service needs and health status were from a survey of AYA cancer survivors. Prevalence of comorbidities was based on the AYA HOPE index. Charlson and NCI indices were compared. Multivariable logistic regression was used. Results: Of the 485 patients, 14.6% had ≥2 comorbidities based on the AYA HOPE Index. Prevalence of mental illness and obesity/overweight, which were not included in existing indices, were 8.2% and 5.8%, respectively. Prevalence of cardiovascular, endocrine, gastrointestinal, and neurologic conditions were higher with the AYA HOPE Index than the other two indices. Forty percent of AYA patients reported service needs, particularly for mental health services (25.2%) and support groups (17.7%). Having ≥2 comorbidities on the AYA index was associated with higher mental health service needs [OR, 2.05; 95% confidence interval (CI), 1.10-3.82] adjusting for demographic and clinical factors. Comorbidities were associated with fair/poor selfreported health status. Conclusion: The AYA HOPE Index is a more comprehensive comorbidity index for AYA cancer patients than existing indices, and the number of comorbidities is associated with service needs and health status. Impact: The AYA HOPE index could identify patients' additional service needs early in therapy. Cancer Epidemiol Biomarkers Prev; 24(12); 1844-9.
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U2 - 10.1158/1055-9965.EPI-15-0401
DO - 10.1158/1055-9965.EPI-15-0401
M3 - Article
C2 - 26420768
AN - SCOPUS:84948738011
SN - 1055-9965
VL - 24
SP - 1844
EP - 1849
JO - Cancer Epidemiology Biomarkers and Prevention
JF - Cancer Epidemiology Biomarkers and Prevention
IS - 12
ER -
