Immunotoxin therapy for CNS tumor

Edward Rustamzadeh, Walter C. Low, Daniel A. Vallera, Walter A. Hall

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Surgery, chemotherapy, and radiation therapy have become standard of practice in treating malignant brain tumors. Unfortunately, the prognosis of these malignant tumors still remains poor. Immunotoxins are a relatively new adjuvant treatment for brain tumors. Within the last few years an increased amount of clinically-oriented research involving immunotoxins has been published. This has led to numerous clinical trials which although encouraging have not yet born out the "magic bullet" concept envisioned for immunotoxins. In this review article the history, design, toxicity, and pharmokinetics of immunotoxins will be discussed in detail.

Original languageEnglish (US)
Pages (from-to)101-116
Number of pages16
JournalJournal of neuro-oncology
Volume64
Issue number1-2
DOIs
StatePublished - Aug 1 2003

Keywords

  • Anaplastic astrocytoma
  • Glioblastoma multiforme
  • Immunotoxin

Fingerprint Dive into the research topics of 'Immunotoxin therapy for CNS tumor'. Together they form a unique fingerprint.

Cite this