Abstract
In Candida albicans, calcineurin mediates tolerance to azole antifungal drugs, survival in serum, and virulence. In this study, we examined 24 Candida isolates from liver transplant recipients receiving a calcineurin inhibitor as a component of their immunosuppressive therapy. We were unable to detect a difference in susceptibility to calcineurin inhibitors in combination with fluconazole, serum, or calcium in these isolates.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1573-1577 |
| Number of pages | 5 |
| Journal | Antimicrobial agents and chemotherapy |
| Volume | 50 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2006 |
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Dive into the research topics of 'Immunotherapy with tacrolimus (FK506) does not select for resistance to calcineurin inhibitors in Candida albicans isolates from liver transplant patients'. Together they form a unique fingerprint.Cite this
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