Abstract
Statement of Purpose: In most types of cancer, the formation of distant metastasis is the point at which clinical treatment shifts from curative intent to palliative care. At present, there is no clinical method to detect metastatic dissemination and colonization of distal sites until radiologically evident, at which point organ function has often already been compromised. The Shea and Jeruss laboratories have developed a biomaterial implant that recruits metastatic cancer cells in xenogeneic human and syngeneic mouse models of breast cancer (1-3). While immune cells associated with the scaffold are associated with recruitment, (2), the relative contributions of individual cytokines to immune cell and subsequent tumor cell recruitment at the pre-metastatic niche is unknown.
Original language | English (US) |
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Title of host publication | Society for Biomaterials Annual Meeting and Exposition 2019 |
Subtitle of host publication | The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting |
Publisher | Society for Biomaterials |
Pages | 109 |
Number of pages | 1 |
ISBN (Electronic) | 9781510883901 |
State | Published - 2019 |
Externally published | Yes |
Event | 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States Duration: Apr 3 2019 → Apr 6 2019 |
Publication series
Name | Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium |
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Volume | 40 |
ISSN (Print) | 1526-7547 |
Conference
Conference | 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence |
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Country/Territory | United States |
City | Seattle |
Period | 4/3/19 → 4/6/19 |
Bibliographical note
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