Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply)

David A. Hafler, Sally C. Kent, Yahua Chen, Lisa Bregoli, Sue M. Clemmings, Hering Bernhard, Kenyon Norma Sue, Ricordi Camillo

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Wilson discusses the avidity of the lymph-node T-cell clones we described that recognize the insulin A1–15 fragment. He questions whether large enough concentrations of insulin would be available in situ for antigenic stimulation of T cells, given the amount of peptide required to stimulate the clones and their degree of responsiveness.

Original languageEnglish (US)
Pages (from-to)E5-E6
Issue number7067
StatePublished - Nov 24 2005


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