Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply)

David A. Hafler, Sally C. Kent, Yahua Chen, Lisa Bregoli, Sue M. Clemmings, Hering Bernhard, Kenyon Norma Sue, Ricordi Camillo

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Wilson discusses the avidity of the lymph-node T-cell clones we described that recognize the insulin A1–15 fragment. He questions whether large enough concentrations of insulin would be available in situ for antigenic stimulation of T cells, given the amount of peptide required to stimulate the clones and their degree of responsiveness.

Original languageEnglish (US)
Pages (from-to)E5-E6
JournalNature
Volume438
Issue number7067
DOIs
StatePublished - Nov 24 2005

Fingerprint Dive into the research topics of 'Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply)'. Together they form a unique fingerprint.

  • Cite this

    Hafler, D. A., Kent, S. C., Chen, Y., Bregoli, L., Clemmings, S. M., Bernhard, H., Norma Sue, K., & Camillo, R. (2005). Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply). Nature, 438(7067), E5-E6. https://doi.org/10.1038/nature04424