Abstract
Some immunologic changes in patients with infective endocarditis were measured during therapy with antibiotics. T cells and C3 levels were low in 29 and 59% of the subjects, respectively. The circulating immune complexes were high and showed a negative correlation with serum C3 levels. Teichoic acid antibodies with titer of above 5 were generally seen only in cases of bacteremia in which endothelial damage had taken place. The antibody was specific for gram-positive organisms because it was negative in gram-negative bacteremia. The antibody showed a fall during treatment and hence could be used to monitor efficacy of antibiotic therapy.
Original language | English (US) |
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Pages (from-to) | 227-232 |
Number of pages | 6 |
Journal | Advances in myocardiology |
Volume | 4 |
DOIs | |
State | Published - 1983 |