Immunologic studies in infective endocarditis.

P. L. Wahi; K. K. Talwar; N. K. Ganguly; A. K. Khanna; P. S. Bidwai; I. S. Anand

doi:10.1007/978-1-4757-4441-5_20

Immunologic studies in infective endocarditis.

P. L. Wahi, K. K. Talwar, N. K. Ganguly, A. K. Khanna, P. S. Bidwai, I. S. Anand

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Article › peer-review

Abstract

Some immunologic changes in patients with infective endocarditis were measured during therapy with antibiotics. T cells and C3 levels were low in 29 and 59% of the subjects, respectively. The circulating immune complexes were high and showed a negative correlation with serum C3 levels. Teichoic acid antibodies with titer of above 5 were generally seen only in cases of bacteremia in which endothelial damage had taken place. The antibody was specific for gram-positive organisms because it was negative in gram-negative bacteremia. The antibody showed a fall during treatment and hence could be used to monitor efficacy of antibiotic therapy.

Original language	English (US)
Pages (from-to)	227-232
Number of pages	6
Journal	Advances in myocardiology
Volume	4
DOIs	https://doi.org/10.1007/978-1-4757-4441-5_20
State	Published - 1983

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title = "Immunologic studies in infective endocarditis.",

abstract = "Some immunologic changes in patients with infective endocarditis were measured during therapy with antibiotics. T cells and C3 levels were low in 29 and 59% of the subjects, respectively. The circulating immune complexes were high and showed a negative correlation with serum C3 levels. Teichoic acid antibodies with titer of above 5 were generally seen only in cases of bacteremia in which endothelial damage had taken place. The antibody was specific for gram-positive organisms because it was negative in gram-negative bacteremia. The antibody showed a fall during treatment and hence could be used to monitor efficacy of antibiotic therapy.",

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AU - Wahi, P. L.

AU - Talwar, K. K.

AU - Ganguly, N. K.

AU - Khanna, A. K.

AU - Bidwai, P. S.

AU - Anand, I. S.

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PY - 1983

Y1 - 1983

N2 - Some immunologic changes in patients with infective endocarditis were measured during therapy with antibiotics. T cells and C3 levels were low in 29 and 59% of the subjects, respectively. The circulating immune complexes were high and showed a negative correlation with serum C3 levels. Teichoic acid antibodies with titer of above 5 were generally seen only in cases of bacteremia in which endothelial damage had taken place. The antibody was specific for gram-positive organisms because it was negative in gram-negative bacteremia. The antibody showed a fall during treatment and hence could be used to monitor efficacy of antibiotic therapy.

AB - Some immunologic changes in patients with infective endocarditis were measured during therapy with antibiotics. T cells and C3 levels were low in 29 and 59% of the subjects, respectively. The circulating immune complexes were high and showed a negative correlation with serum C3 levels. Teichoic acid antibodies with titer of above 5 were generally seen only in cases of bacteremia in which endothelial damage had taken place. The antibody was specific for gram-positive organisms because it was negative in gram-negative bacteremia. The antibody showed a fall during treatment and hence could be used to monitor efficacy of antibiotic therapy.

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Immunologic studies in infective endocarditis.

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