Abstract
Renal tissue from 12 dogs with spontaneous diabetes and 16 control dogs were studied by light, immunofluorescence, and electron microscopies. Significant linear staining for immunoglobulin G and albumin were observed in the glomerular and tubular basement membranes of dogs with spontaneous diabetes--similar to that observed in human diabetes. On immunohistochemical grounds, it would appear that the dog with spontaneous diabetes is an appropriate model of diabetes in persons.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1162-1165 |
| Number of pages | 4 |
| Journal | American journal of veterinary research |
| Volume | 45 |
| Issue number | 6 |
| State | Published - Jun 1 1984 |
