Immunofluorescence in Robotic Colon and Rectal Surgery

Matthew C. Bobel, Ariella Altman, Wolfgang B. Gaertner

Research output: Contribution to journalReview articlepeer-review


The indocyanine green fluorescence imaging system is a surgical tool with increasing applications in colon and rectal surgery that has received growing acceptance in various surgical disciplines as a potentially valid method to enhance surgical field visualization, improve lymph node retrieval, and decrease anastomotic leak. Small noncomparative prospective trials have shown that intraoperative fluorescence imaging is a safe and feasible method to assess anastomotic perfusion and that its use may impact anastomotic leak rates. However, larger prospective and randomized studies are required to validate its role and impact in colorectal surgery. The purpose of this article is to review the current status of the use of immunofluorescence in colon and rectal surgery, as well as new applications in robotic colon and rectal resections.

Original languageEnglish (US)
Article number01087
Pages (from-to)338-344
Number of pages7
JournalClinics in Colon and Rectal Surgery
Issue number5
StatePublished - Sep 1 2021

Bibliographical note

Publisher Copyright:
© 2021 Thieme Medical Publishers, Inc.. All rights reserved.


  • Firefly
  • immunofluorescence
  • indocyanine green
  • robotic colorectal surgery

PubMed: MeSH publication types

  • Journal Article
  • Review


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