Immunization of suckling pigs against enterotoxigenic Escherichia coli-induced diarrheal disease by vaccinating dams with purified K99 or 987P Pili: Antibody production in response to vaccination

R. E. Isaacson, E. A. Dean, R. L. Morgan, H. W. Moon

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Pilus-specific antibody levels measured by enzyme-linked immunosorbent assays in serum and colostrum of pregnant swine (dams) were shown to increase after parenteral vaccination with pili. Pilus-specific antibody levels in dams were correlated with protection of their suckling offspring against fatal diarrhea caused by enterotoxigenic Escherichia coli possessing the same pilus as the vaccine.

Original languageEnglish (US)
Pages (from-to)824-826
Number of pages3
JournalInfection and Immunity
Volume29
Issue number2
StatePublished - Jan 1 1980

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