Immunization against bovine papillomavirus infection.

W. P. Pilacinski; D. L. Glassman; K. F. Glassman; D. E. Reed; M. A. Lum; R. F. Marshall; C. C. Muscoplat; A. J. Faras

Immunization against bovine papillomavirus infection.

W. P. Pilacinski, D. L. Glassman, K. F. Glassman, D. E. Reed, M. A. Lum, R. F. Marshall, C. C. Muscoplat, A. J. Faras

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Abstract

The two large open reading frames denoted L1 and L2 in the non-transforming region of the bovine papillomavirus type 1 (BPV-1) genome have been molecularly cloned to expression in Escherichia coli. Antisera against the E. coli-derived L1 and L2 protein reacted with BPV-1 in both enzyme-linked immunosorbent assays and immunoprecipitation reactions. Neutralization of BPV-induced transformation of mouse C127 cells was demonstrated most consistently with antisera against the L1 protein. E. coli-derived L1 protein protected calves against BPV-1 challenge after vaccination.

Original language	English (US)
Pages (from-to)	136-156
Number of pages	21
Journal	Ciba Foundation symposium
Volume	120
State	Published - 1986

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title = "Immunization against bovine papillomavirus infection.",

abstract = "The two large open reading frames denoted L1 and L2 in the non-transforming region of the bovine papillomavirus type 1 (BPV-1) genome have been molecularly cloned to expression in Escherichia coli. Antisera against the E. coli-derived L1 and L2 protein reacted with BPV-1 in both enzyme-linked immunosorbent assays and immunoprecipitation reactions. Neutralization of BPV-induced transformation of mouse C127 cells was demonstrated most consistently with antisera against the L1 protein. E. coli-derived L1 protein protected calves against BPV-1 challenge after vaccination.",

author = "Pilacinski, \{W. P.\} and Glassman, \{D. L.\} and Glassman, \{K. F.\} and Reed, \{D. E.\} and Lum, \{M. A.\} and Marshall, \{R. F.\} and Muscoplat, \{C. C.\} and Faras, \{A. J.\}",

year = "1986",

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journal = "Ciba Foundation symposium",

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T1 - Immunization against bovine papillomavirus infection.

AU - Pilacinski, W. P.

AU - Glassman, D. L.

AU - Glassman, K. F.

AU - Reed, D. E.

AU - Lum, M. A.

AU - Marshall, R. F.

AU - Muscoplat, C. C.

AU - Faras, A. J.

PY - 1986

Y1 - 1986

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AB - The two large open reading frames denoted L1 and L2 in the non-transforming region of the bovine papillomavirus type 1 (BPV-1) genome have been molecularly cloned to expression in Escherichia coli. Antisera against the E. coli-derived L1 and L2 protein reacted with BPV-1 in both enzyme-linked immunosorbent assays and immunoprecipitation reactions. Neutralization of BPV-induced transformation of mouse C127 cells was demonstrated most consistently with antisera against the L1 protein. E. coli-derived L1 protein protected calves against BPV-1 challenge after vaccination.

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SN - 0300-5208

VL - 120

SP - 136

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JO - Ciba Foundation symposium

JF - Ciba Foundation symposium

ER -

Immunization against bovine papillomavirus infection.

Abstract

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