Immune functions of cord blood cells before and after transplantation

Maria Grazia Roncarolo; Mike Bigler; Silvana Martino; Eliana Ciuti; Pier Angelo Tovo; John E Wagner

Immune functions of cord blood cells before and after transplantation

Maria Grazia Roncarolo
, Mike Bigler
, Silvana Martino
, Eliana Ciuti
, Pier Angelo Tovo
, John E Wagner

Pediatric Blood & Marrow Transplant & Cellular Therapy

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

There have been numerous reports of decreased acute and chronic graft-versus-host disease in patients receiving HLA-matched or HLA-disparate umbilical cord transplants. It has been proposed that this may be due to the unique properties of the neonatal immune system, which permit the development of tolerance to alloantigens. This review discusses experimental evidence contrasting the immune functions of cells derived from cord blood and those from peripheral blood.

Original language	English (US)
Pages (from-to)	157-160
Number of pages	4
Journal	Journal of Hematotherapy and Stem Cell Research
Volume	5
Issue number	2
State	Published - Apr 1 1996

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Find It

Find It at U of M Libraries

Cite this

@article{5b892a799def4704ada7a8b4317f776f,

title = "Immune functions of cord blood cells before and after transplantation",

abstract = "There have been numerous reports of decreased acute and chronic graft-versus-host disease in patients receiving HLA-matched or HLA-disparate umbilical cord transplants. It has been proposed that this may be due to the unique properties of the neonatal immune system, which permit the development of tolerance to alloantigens. This review discusses experimental evidence contrasting the immune functions of cells derived from cord blood and those from peripheral blood.",

author = "Roncarolo, \{Maria Grazia\} and Mike Bigler and Silvana Martino and Eliana Ciuti and Tovo, \{Pier Angelo\} and Wagner, \{John E\}",

year = "1996",

month = apr,

day = "1",

language = "English (US)",

volume = "5",

pages = "157--160",

journal = "Journal of Hematotherapy and Stem Cell Research",

issn = "1525-8165",

publisher = "SAGE Publications Ltd",

number = "2",

}

TY - JOUR

T1 - Immune functions of cord blood cells before and after transplantation

AU - Roncarolo, Maria Grazia

AU - Bigler, Mike

AU - Martino, Silvana

AU - Ciuti, Eliana

AU - Tovo, Pier Angelo

AU - Wagner, John E

PY - 1996/4/1

Y1 - 1996/4/1

N2 - There have been numerous reports of decreased acute and chronic graft-versus-host disease in patients receiving HLA-matched or HLA-disparate umbilical cord transplants. It has been proposed that this may be due to the unique properties of the neonatal immune system, which permit the development of tolerance to alloantigens. This review discusses experimental evidence contrasting the immune functions of cells derived from cord blood and those from peripheral blood.

AB - There have been numerous reports of decreased acute and chronic graft-versus-host disease in patients receiving HLA-matched or HLA-disparate umbilical cord transplants. It has been proposed that this may be due to the unique properties of the neonatal immune system, which permit the development of tolerance to alloantigens. This review discusses experimental evidence contrasting the immune functions of cells derived from cord blood and those from peripheral blood.

UR - https://www.scopus.com/pages/publications/0029877590

UR - https://www.scopus.com/pages/publications/0029877590#tab=citedBy

M3 - Article

C2 - 8723794

AN - SCOPUS:0029877590

SN - 1525-8165

VL - 5

SP - 157

EP - 160

JO - Journal of Hematotherapy and Stem Cell Research

JF - Journal of Hematotherapy and Stem Cell Research

IS - 2

ER -

Immune functions of cord blood cells before and after transplantation

Abstract

UN SDGs

Find It

Other files and links

Fingerprint

Cite this