Imaging of the Vasa Nervorum Using Contrast-Enhanced Ultrasound

Adnan I. Qureshi, Muhammad A. Saleem, Asad Ahrar, Faisal Raja

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


INTRODUCTION: We describe the use of intravenous contrast-enhanced ultrasonography to study vasa nervorum using contrast-enhanced ultrasound. METHODS: We imaged the median, femoral, or sciatic nerves in 4 patients in longitudinal plane using high-resolution ultrasound after intravenous bolus of activated Perflutren lipid microspheres. The images were acquired as photopic images (in brown color) in real time using 2-dimensional B-Flow mode scan within a selected region of interest. RESULTS: The vasa nervorum was seen as focal ovoid enhancement along either the superior and inferior aspects of the nerve most pronounced during arterial phase (peak enhancement) in all 4 patients. The fluctuating intensity of enchancement during cardiac cycle confirmed the arterial origin of enhacement. Punctate, linear, or diffuse enhancement was also seen along the trunk of the nerve. CONCLUSIONS: We were able to identify the vasa nervorum along the outer aspect of the studied nerves using contrast-enhanced ultrasound.

Original languageEnglish (US)
Pages (from-to)583-588
Number of pages6
JournalJournal of Neuroimaging
Issue number6
StatePublished - Nov 1 2017

Bibliographical note

Publisher Copyright:
Copyright © 2017 by the American Society of Neuroimaging


  • Nerve perfusion
  • contrast
  • lipid microspheres
  • nerve ischemia
  • neuropathy
  • ultrasonography
  • vasa nervorum


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