Abstract
We have immobilized chemically-fixed cellular microtubules and microtubule protein polymers on glow-discharged glass discs for scanning by atomic force microscopy (AFM). The images obtained by AFM resembled those obtained by conventional transmission electron microscopy of the same material. The AFM images can resolve some of the surface features of microtubules to 10 nm. Improvements in the techniques promise resolution approaching molecular dimensions.
Original language | English (US) |
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Title of host publication | Proceedings of SPIE - The International Society for Optical Engineering |
Publisher | Publ by Int Soc for Optical Engineering |
Pages | 138-144 |
Number of pages | 7 |
Volume | 1639 |
ISBN (Print) | 0819407852 |
State | Published - Jan 1 1992 |
Event | Scanning Probe Microscopies - Los Angeles, CA, USA Duration: Jan 20 1992 → Jan 22 1992 |
Other
Other | Scanning Probe Microscopies |
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City | Los Angeles, CA, USA |
Period | 1/20/92 → 1/22/92 |