Image-guided phased array system for ultrasound thermotherapy

P. VanBaren, C. Simon, R. Seip, T. Solf, C. A. Cain, E. S. Ebbini

Research output: Contribution to journalConference articlepeer-review

19 Scopus citations


An image-guided ultrasonic phased array system for non-invasive tissue ablation is described. Image guidance is provided by processing beamformed RF-data from a commercially available scanner. Two dimensional estimates of tissue temperature are obtained in real-time by implementing a high-speed displacement tracking algorithm. Experimental results validate our approach for image guidance in which the therapy array is initially driven at low (non-destructive) intensity sufficient to cause a small change in temperature at the focus. Two-dimensional non-invasive temperature data is then used to localize and assess the quality of the focus. If the extent and location of the focal spot are consistent with expected values, a high-intensity pulse capable of causing tissue ablation is delivered. Preliminary in-vitro beef muscle experiments are reported, showing successful visualization of the location and quality of the HIFU focus followed by an ablative pulse. Dissection revealed lesion formation (approx.2mm dia., 12mm long, 30mm deep within the tissue) at the expected location.

Original languageEnglish (US)
Pages (from-to)1269-1272
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
StatePublished - Dec 1 1996
EventProceedings of the 1996 IEEE Ultrasonics Symposium. Part 2 (of 2) - San Antonio, TX, USA
Duration: Nov 3 1996Nov 6 1996


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