Image-based multiscale modeling predicts tissue-level and network-level fiber reorganization in stretched cell-compacted collagen gels

Keyphrases

• Multiscale Modeling 100%
• Cell Signaling 100%
• Extracellular Matrix 100%
• Image-based 100%
• Network Level 100%
• Collagen Gel 100%
• Tissue Level 100%
• Stretched Cells 100%
• Mechanical Properties 50%
• Heterogeneous Networks 50%
• Anisotropy 50%
• Network Change 50%
• Cellular Response 50%
• Modeling Techniques 50%
• Mechanical Testing 50%
• Tissue Homeostasis 50%
• Fiber Network 50%
• Structure Level 50%
• Applied Load 50%
• Non-affine 50%
• Extracellular Matrix Organization 50%
• Biaxial Extension 50%
• Macroscopic Displacement 50%
• Multiscale Interactions 50%
• Matrix Heterogeneity 50%
• Mechanical Microenvironment 50%

Engineering

• Multiscale Modeling 100%
• Multiscale Model 100%
• Network Level 100%
• Multiscale 50%
• Multiple Scale 50%
• Tensiles 50%
• Mechanical Environment 50%
• Fine Detail 50%
• Matrix Structure 50%
• Cellular Response 50%
• Tissue Homeostasis 50%
• Externally Applied Load 50%
• Heterogeneous Network 50%