Idiopathic pulmonary hemosiderosis. Ultrastructural studies and response to azathioprine

H. Yeager, D. Powell, R. M. Weinberg, H. Bauer, J. A. Bellanti, S. Katz

Research output: Contribution to journalArticle

Abstract

Two boys are presented who fulfulled criteria for a diagnosis of idiopathic pulmonary hemosiderosis. A lung biopsy specimen from the first patient showed alveolar capillary basement membrane abnormalities, together with abnormalities of capillary endothelial cells and hemosiderin laden macrophages. A lung biopsy specimen from the second patient showed mainly capillary endothelial abnormalities and interstitial fibrosis. Both patients had a noticeable improvement in symptoms and relative stabilization of their roentgenographic and pulmonary function abnormalities following azathioprine therapy.

Original languageEnglish (US)
Pages (from-to)1145-1149
Number of pages5
JournalArchives of Internal Medicine
Volume136
Issue number10
DOIs
StatePublished - Dec 1 1976

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Azathioprine
Lung
Hemosiderin
Biopsy
Basement Membrane
Fibrosis
Endothelial Cells
Macrophages
Idiopathic pulmonary hemosiderosis
Therapeutics

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Idiopathic pulmonary hemosiderosis. Ultrastructural studies and response to azathioprine. / Yeager, H.; Powell, D.; Weinberg, R. M.; Bauer, H.; Bellanti, J. A.; Katz, S.

In: Archives of Internal Medicine, Vol. 136, No. 10, 01.12.1976, p. 1145-1149.

Research output: Contribution to journalArticle

Yeager, H. ; Powell, D. ; Weinberg, R. M. ; Bauer, H. ; Bellanti, J. A. ; Katz, S. / Idiopathic pulmonary hemosiderosis. Ultrastructural studies and response to azathioprine. In: Archives of Internal Medicine. 1976 ; Vol. 136, No. 10. pp. 1145-1149.
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