Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery

Christa Hamashin; Lisa Spindler; Shannon Russell; Amy Schink; Imelda Lambkin; Daniel O'Mahony; Richard Houghten; Clemencia Pinilla

doi:10.1016/j.bmc.2003.09.002

Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery

Christa Hamashin
, Lisa Spindler
, Shannon Russell
, Amy Schink
, Imelda Lambkin
, Daniel O'Mahony
, Richard Houghten
, Clemencia Pinilla

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Lectin mimetics have been identified that may have potential application towards targeted drug delivery. Synthetic multivalent polygalloyl constructs effectively competed with Ulex europaeus agglutinin I (UEA1) for binding to intestinal Caco-2 cell membranes.

Original language	English (US)
Pages (from-to)	4991-4997
Number of pages	7
Journal	Bioorganic and Medicinal Chemistry
Volume	11
Issue number	23
DOIs	https://doi.org/10.1016/j.bmc.2003.09.002
State	Published - Nov 17 2003
Externally published	Yes

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10.1016/j.bmc.2003.09.002

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@article{d054a39172d94ed29194a86d08cb35d9,

title = "Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery",

abstract = "Lectin mimetics have been identified that may have potential application towards targeted drug delivery. Synthetic multivalent polygalloyl constructs effectively competed with Ulex europaeus agglutinin I (UEA1) for binding to intestinal Caco-2 cell membranes.",

author = "Christa Hamashin and Lisa Spindler and Shannon Russell and Amy Schink and Imelda Lambkin and Daniel O'Mahony and Richard Houghten and Clemencia Pinilla",

year = "2003",

month = nov,

day = "17",

doi = "10.1016/j.bmc.2003.09.002",

language = "English (US)",

volume = "11",

pages = "4991--4997",

journal = "Bioorganic and Medicinal Chemistry",

issn = "0968-0896",

publisher = "Elsevier Ltd",

number = "23",

}

TY - JOUR

T1 - Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery

AU - Hamashin, Christa

AU - Spindler, Lisa

AU - Russell, Shannon

AU - Schink, Amy

AU - Lambkin, Imelda

AU - O'Mahony, Daniel

AU - Houghten, Richard

AU - Pinilla, Clemencia

PY - 2003/11/17

Y1 - 2003/11/17

N2 - Lectin mimetics have been identified that may have potential application towards targeted drug delivery. Synthetic multivalent polygalloyl constructs effectively competed with Ulex europaeus agglutinin I (UEA1) for binding to intestinal Caco-2 cell membranes.

AB - Lectin mimetics have been identified that may have potential application towards targeted drug delivery. Synthetic multivalent polygalloyl constructs effectively competed with Ulex europaeus agglutinin I (UEA1) for binding to intestinal Caco-2 cell membranes.

UR - https://www.scopus.com/pages/publications/0242329793

UR - https://www.scopus.com/pages/publications/0242329793#tab=citedBy

U2 - 10.1016/j.bmc.2003.09.002

DO - 10.1016/j.bmc.2003.09.002

M3 - Article

C2 - 14604661

AN - SCOPUS:0242329793

SN - 0968-0896

VL - 11

SP - 4991

EP - 4997

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

IS - 23

ER -

Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery

Abstract

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