Identification of novel small-molecule Ulex europaeus I mimetics for targeted drug delivery

Christa Hamashin, Lisa Spindler, Shannon Russell, Amy Schink, Imelda Lambkin, Daniel O'Mahony, Richard Houghten, Clemencia Pinilla

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Lectin mimetics have been identified that may have potential application towards targeted drug delivery. Synthetic multivalent polygalloyl constructs effectively competed with Ulex europaeus agglutinin I (UEA1) for binding to intestinal Caco-2 cell membranes.

Original languageEnglish (US)
Pages (from-to)4991-4997
Number of pages7
JournalBioorganic and Medicinal Chemistry
Volume11
Issue number23
DOIs
StatePublished - Nov 17 2003
Externally publishedYes

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